| MIDWEST REGION |
| Host - Varies |
| Regional Twitter - @DI_Midwest_Reg |
| Regional Gear - shopnccaa.com |
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| TIME (ET) / GAME |
MATCHUP |
| Saturday, November 12, 2022 |
| 6:00pm / Game 1 (at Geneva) |
#5 Redeemer University def. #4 Geneva College 2-1 |
| Video | Stats | Box Score |
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| Monday, November 14, 2022 |
| 2:00pm / Semi 1 (at Cedarville) |
#2 Cedarville University def. #3 Lancaster Bible College 4-0 |
| Video | Stats | Box Score |
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| Tuesday, November 15, 2022 |
| 7:30pm / Semi 2 (at Roberts Wesleyan) |
#1 Roberts Wesleyan University def. #5 Redeemer University 6-2 |
| Video | Stats | Box Score |
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| Roberts Wesleyan University declared Midwest Regional Qualifier. Cedarville University will accept an at-large bid. |